Goldblatt’s Early Hypertension Research

A $1,000 grant advanced the highly significant hypertension research of Harry Goldblatt, M.D., director of Western Reserve University’s Institute of Pathology. Goldblatt’s experiments in the 1930s provided a partial answer to clinicians’ bafflement about the causes of hypertension. He demonstrated that if a portion of the main arteries to the kidneys was clamped, blood pressure rose. Goldblatt won international acclaim for his subsequent research identifying elevated levels of renin, an enzyme that regulates arterial blood pressure, as a factor contributing to hypertension.
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